1 Me: {looking at a graph on computer screen} Hmmm, this is interesting.
2 Me: A histogram of the distribution of annual number of deaths due to improperly prepared fugu in Japan.
3 Me: Interesting stats, but I don't understand why people would risk eating such a dangerous food.
4 Me: I guess one man's fish is another man's poisson.

Okay, to fully get this one you need knowledge of:

• Japanese cuisine. Fugu is a genus of puffer fish, regarded by many Japanese as a delicacy. Unfortunately, its liver and other organs contain lethal concentrations of the highly toxic tetrodotoxin. This is normally removed by the specially trained and licensed chefs who are the only ones allowed to prepare the fish for consumption. But sometimes mistakes are made, and some poison remains in the prepared dish. Diners eating it feel a tingling sensation, followed by paralysis, and death. There is no cure, and a few people die this way in Japan each year.
• French language. Poisson is French for "fish".
• Statistics. The Poisson distribution is a statistical distribution first described by Siméon-Denis Poisson, a French mathematician who lived from 1781 to 1840. The distribution describes the expected number of events of a fixed probability occurring within a fixed interval of time - such as the expected number of deaths due to fugu poisoning in Japan in a year.

Et voilà!

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As pointed out by a reader, the graph shown on the screen in this strip is in fact not strictly a histogram, but a bar graph. The difference is that the bars in a histogram always abut each other without any gap in between. Dealing with histograms for my work on frequent occasions, I should certainly have not confused them. I think I in fact tried to make a histogram, but was defeated by good old Microsoft Excel's stupid graph formatting functions.